Should I stop my dog's joint supplement when starting gabapentin?

Gabapentin for nerve pain is a different lane entirely from joint supplementation — it acts on the nervous system's pain transmission, not the joint itself. There's no known interaction between gabapentin and standard joint supplements. Did the vet ask about what supplements he's currently on when prescribing it?

Your vet is right — continue the YuMOVE Senior alongside the gabapentin. They address completely different aspects of his pain: the gabapentin manages the neuropathic pain signal; the YuMOVE Senior supports the joint tissue that's generating the inflammatory input to that system. Stopping the supplement now would remove the cartilage and anti-inflammatory support without any benefit. Run both as directed, keep an eye on his mobility over the next 4–6 weeks, and the combination should give you a meaningfully clearer picture of his quality of life than either alone.